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DOV 21947 hydrochloride

CAS No. 410074-74-7

DOV 21947 hydrochloride ( Amitifadine hydrochloride )

Catalog No. M14409 CAS No. 410074-74-7

Amitifadine hydrochloride is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DOV 21947 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Amitifadine hydrochloride is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
  • Description
    Amitifadine hydrochloride is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). Ki values for SERT/NET/ DAT are 99/262/213 nM. The IC50 values for serotonin, norepinephrine and dopamine reuptake are 12/23/96 nM.
  • Synonyms
    Amitifadine hydrochloride
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT; Dopamine; Norepinephrine (NE)
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    410074-74-7
  • Formula Weight
    264.58
  • Molecular Formula
    C11H12Cl3N
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    C1[C@H]2[C@@]1(CNC2)C3=CC(=C(C=C3)Cl)Cl.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Skolnick P, et al. Eur J Pharmacol. 2003 Feb 14;461(2-3):99-104.
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